FRS2 抗体 (AA 162-211)
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北京 101111
Quick Overview for FRS2 抗体 (AA 162-211) (ABIN1533121)
抗原
See all FRS2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 162-211
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原理
- FRS2 Antibody
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特异性
- FRS2 Polyclonal Antibody detects endogenous levels of FRS2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human FRS2. AA range:162-211
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亚型
- IgG
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anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr580) antibody
FRS2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人, 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 239-449) antibodyFRS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (Tyr196) antibodyFRS2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) antibodyFRS2 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5785 unconjugated Recombinant Antibody
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (C-Term) antibodyFRS2 适用: 人, 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal AFfirm8954 unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (AA 1-341) antibodyFRS2 适用: 人 WB 宿主: 小鼠 Monoclonal 1F7-1D6 unconjugated
anti-Fibroblast Growth Factor Receptor Substrate 2 (FRS2) (pTyr436) antibodyFRS2 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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别名
- FRS2
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背景
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Synonyms: FRS2, Fibroblast growth factor receptor substrate 2, FGFR substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1
Background: function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.,PTM:Phosphorylated on tyrosine residues upon stimulation by NGF.,PTM:Ubiquitinated when tyrosine phosphorylated and in a complex with GRB2. The unphosphorylated form is not subject to ubiquitination.,sequence caution:Translated as stop.,similarity:Contains 1 IRS-type PTB domain.,subcellular location:Cytoplasmic, membrane-bound.,subunit:Part of a complex containing FRS2, GRB2 and SOS1. Part of a complex containing GRB2 and CBL. Binds RET (By similarity). Binds FGFR1, SUC1, NTRK1, NTRK2, NTRK3 and SRC. The tyrosine-phosphorylated protein binds the SH2 domains of GRB2 and PTPN11.,tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.,
Gene Name: FRS2
Protein Name: Fibroblast growth factor receptor substrate 2
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分子量
- 57 kDa
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基因ID
- 10818
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OMIM
- 607743
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UniProt
- Q8WU20
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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