MAP3K8 抗体 (AA 366-415)
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北京 101111
Quick Overview for MAP3K8 抗体 (AA 366-415) (ABIN1533088)
抗原
See all MAP3K8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 366-415
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原理
- Cot Antibody
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特异性
- Cot Polyclonal Antibody detects endogenous levels of Cot protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MAP3K8. AA range:366-415
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亚型
- IgG
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应用备注
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))
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别名
- MAP3K8
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背景
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Synonyms: MAP3K8, COT, ESTF, Mitogen-activated protein kinase kinase kinase 8, Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2, TPL-2
Background: ectopic P-granules autophagy protein 5 homolog(EPG5) Homo sapiens This gene encodes a large coiled coil domain-containing protein that functions in autophagy during starvation conditions. Mutations in this gene cause Vici syndrome. [provided by RefSeq, Aug 2015],
Gene Name: MAP3K8
Protein Name: Mitogen-activated protein kinase kinase kinase 8
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分子量
- 52 kDa
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OMIM
- 191195
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UniProt
- P41279
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途径
- PI3K-Akt Signaling, TCR Signaling
抗原
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