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EIF2A 抗体 (AA 21-70)

The 兔 多克隆 anti-EIF2A antibody (ABIN1532855) specifically detects EIF2A in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 大鼠, 小鼠, 猴 和 鱼 samples.
产品编号 ABIN1532855
发货至: 中国
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Quick Overview for EIF2A 抗体 (AA 21-70) (ABIN1532855)

抗原

See all EIF2A 抗体
EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

适用

  • 136
  • 73
  • 62
  • 9
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
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  • 1
人, 大鼠, 小鼠, 猴, 鱼

宿主

  • 116
  • 20
  • 2
兔

克隆类型

  • 83
  • 55
多克隆

标记

  • 68
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
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  • 2
  • 2
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
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This EIF2A antibody is un-conjugated

应用范围

  • 119
  • 75
  • 55
  • 55
  • 42
  • 23
  • 15
  • 14
  • 10
  • 6
  • 3
  • 2
  • 2
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

    • 20
    • 17
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-70

    原理

    eIF2α Antibody

    特异性

    EIF2α Polyclonal Antibody detects endogenous levels of eIF2α protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human eIF2 alpha. AA range:21-70

    亚型

    IgG
  • 应用备注

    IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    EIF2A (Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A))

    别名

    eIF2 alpha

    背景

    Synonyms: EIF2S1, EIF2A, Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit alpha, eIF-2-alpha, eIF-2A, eIF-2alpha

    Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2, MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010],

    Gene Name: EIF2S1

    Protein Name: Eukaryotic translation initiation factor 2 subunit 1

    分子量

    36 kDa

    基因ID

    1965

    OMIM

    603907

    UniProt

    P05198

    途径

    Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
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