DUSP1 抗体 (AA 318-367)
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Quick Overview for DUSP1 抗体 (AA 318-367) (ABIN1532716)
抗原
See all DUSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 318-367
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原理
- MKP-1 Antibody
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特异性
- MKP-1 Polyclonal Antibody detects endogenous levels of MKP-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MKP1. AA range:318-367
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亚型
- IgG
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anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibody
Verified DUSP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 151-250) antibodyDUSP1 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (Ser296), (Ser318) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 305-367) antibodyDUSP1 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 4H7 unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (AA 87-101), (C-Term) antibodyDUSP1 适用: 人, 大鼠, 犬 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (C-Term) antibodyDUSP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (pSer296), (pSer318) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dual Specificity Phosphatase 1 (DUSP1) (Ser31) antibodyDUSP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))
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别名
- MKP1
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背景
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Synonyms: DUSP1, CL100, MKP1, PTPN10, VH1, Dual specificity protein phosphatase 1, Dual specificity protein phosphatase hVH1, Mitogen-activated protein kinase phosphatase 1, MAP kinase phosphatase 1, MKP-1, Protein-tyrosine phosphatase CL100
Background: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferati
Gene Name: DUSP1
Protein Name: Dual specificity protein phosphatase 1
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分子量
- 39 kDa
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基因ID
- 1843
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OMIM
- 600714
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UniProt
- P28562
抗原
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