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IL2 Receptor beta 抗体 (AA 331-380)

This 兔 多克隆 antibody specifically detects IL2 Receptor beta in WB, ELISA 和 IF. It exhibits reactivity toward 小鼠, 人 和 大鼠.
产品编号 ABIN1532688
发货至: 中国
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Room 801-803
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Quick Overview for IL2 Receptor beta 抗体 (AA 331-380) (ABIN1532688)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

  • 127
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  • 1
小鼠, 人, 大鼠

宿主

  • 113
  • 41
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  • 1
兔

克隆类型

  • 112
  • 77
  • 2
多克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 29
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    AA 331-380

    原理

    IL-2Rβ Antibody

    特异性

    IL-2Rβ Polyclonal Antibody detects endogenous levels of IL-2Rβ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human IL-2R beta. AA range:331-380

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    IL-2R beta

    背景

    Synonyms: IL2RB, Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, p75, CD antigen CD122

    Background: The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an up

    Gene Name: IL2RB

    Protein Name: Interleukin-2 receptor subunit beta

    分子量

    61 kDa

    基因ID

    3560

    OMIM

    146710

    UniProt

    P14784

    途径

    JAK/STAT Signaling, Growth Factor Binding
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