PPARA 抗体 (AA 6-55)
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Quick Overview for PPARA 抗体 (AA 6-55) (ABIN1532643)
抗原
See all PPARA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 6-55
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原理
- PPAR-α Antibody
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特异性
- PPAR-α Polyclonal Antibody detects endogenous levels of PPAR-α protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PPAR-alpha. AA range:6-55
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亚型
- IgG
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应用备注
- WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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别名
- PPAR-alpha
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背景
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Synonyms: PPARA, NR1C1, PPAR, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1
Background: peroxisome proliferator activated receptor alpha(PPARA) Homo sapiens Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified.This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for thi
Gene Name: PPARA
Protein Name: Peroxisome proliferator-activated receptor alpha
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分子量
- 52 kDa
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基因ID
- 5465
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OMIM
- 170998
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UniProt
- Q07869
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途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
抗原
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