BMX 抗体 (AA 532-581)
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北京 101111
Quick Overview for BMX 抗体 (AA 532-581) (ABIN1532513)
抗原
See all BMX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 532-581
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原理
- Bmx Antibody
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特异性
- Bmx Polyclonal Antibody detects endogenous levels of Bmx protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human C-ternal ETK. AA range:532-581
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BMX (BMX Non-Receptor Tyrosine Kinase (BMX))
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别名
- ETK
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背景
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Synonyms: BMX, Cytoplasmic tyrosine-protein kinase BMX, Bone marrow tyrosine kinase gene in chromosome X protein, Epithelial and endothelial tyrosine kinase, ETK, NTK38
Background: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],
Gene Name: BMX
Protein Name: Cytoplasmic tyrosine-protein kinase BMX
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分子量
- 78 kDa
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基因ID
- 660
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OMIM
- 300101
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UniProt
- P51813
抗原
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