PKC delta 抗体 (AA 471-520)
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Quick Overview for PKC delta 抗体 (AA 471-520) (ABIN483094)
抗原
See all PKC delta (PKCd) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-520
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原理
- PKC δ Antibody
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特异性
- PKC δ Polyclonal Antibody detects endogenous levels of PKC δ protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PKC delta. AA range:471-520
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亚型
- IgG
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应用备注
- Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
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别名
- PKC delta
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背景
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Synonyms: PRKCD, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta
Background: p21 (RAC1) activated kinase 2(PAK2) Homo sapiens The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities.The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008],
Gene Name: PRKCD
Protein Name: Protein kinase C delta type
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分子量
- 77 kDa
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OMIM
- 176977
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UniProt
- Q05655
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途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
抗原
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