Tuberin 抗体 (AA 905-954)
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北京 101111
Quick Overview for Tuberin 抗体 (AA 905-954) (ABIN1532423)
抗原
See all Tuberin (TSC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 905-954
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原理
- Tuberin Antibody
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特异性
- Tuberin Polyclonal Antibody detects endogenous levels of Tuberin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Tuberin/TSC2. AA range:905-954
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
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别名
- Tuberin/TSC2
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背景
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Synonyms: TSC2, TSC4, Tuberin, Tuberous sclerosis 2 protein
Background: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Gene Name: TSC2
Protein Name: Tuberin
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分子量
- 200 kDa
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基因ID
- 7249
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OMIM
- 191092
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UniProt
- P49815
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途径
- RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
抗原
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