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alpha Adducin 抗体 (AA 411-460)

This 兔 多克隆 antibody specifically detects alpha Adducin in IHC, ELISA 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1532315
发货至: 中国
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Room 801-803
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Quick Overview for alpha Adducin 抗体 (AA 411-460) (ABIN1532315)

抗原

See all alpha Adducin (ADD1) 抗体
alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

适用

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人, 小鼠, 大鼠

宿主

  • 90
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兔

克隆类型

  • 89
  • 4
多克隆

标记

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This alpha Adducin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 411-460

    原理

    ADD1 Antibody

    特异性

    ADD1 Polyclonal Antibody detects endogenous levels of ADD1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human ADD1. AA range:411-460

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

    别名

    ADD1

    背景

    Synonyms: ADD1, ADDA, Alpha-adducin, Erythrocyte adducin subunit alpha

    Background: adducin 1(ADD1) Homo sapiens Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described. [provided by RefSeq, Jul 2008],

    Gene Name: ADD1

    Protein Name: Alpha-adducin

    分子量

    80 kDa

    基因ID

    118

    OMIM

    102680

    UniProt

    P35611

    途径

    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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