HDAC5 抗体 (AA 225-274)
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Quick Overview for HDAC5 抗体 (AA 225-274) (ABIN1532301)
抗原
See all HDAC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 225-274
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原理
- HDAC5/9 Antibody
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特异性
- HDAC5/9 Polyclonal Antibody detects endogenous levels of HDAC5/9 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HDAC5. AA range:225-274
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HDAC5 (Histone Deacetylase 5 (HDAC5))
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别名
- HDAC5
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背景
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Synonyms: HDAC5, KIAA0600, Histone deacetylase 5, HD5, Antigen NY-CO-9, HDAC9, HDAC7, HDAC7B, HDRP, KIAA0744, MITR, Histone deacetylase 9, HD9, Histone deacetylase 7B, HD7, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription rep
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: HDAC5/HDAC9
Protein Name: Histone deacetylase 5/9
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分子量
- 121 kDa
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基因ID
- 10014, 9734
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OMIM
- 605315
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UniProt
- Q9UQL6
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
抗原
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