ZYX 抗体 (pSer142)
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北京 101111
Quick Overview for ZYX 抗体 (pSer142) (ABIN1532180)
抗原
See all ZYX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-157, pSer142
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原理
- Zyxin (phospho Ser142) Antibody
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特异性
- Phospho-Zyxin (S142) Polyclonal Antibody detects endogenous levels of Zyxin protein only when phosphorylated at S142.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Zyxin around the phosphorylation site of Ser142. AA range:108-157
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亚型
- IgG
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anti-Zyxin (ZYX) (AA 1-572) antibody
ZYX 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2C10-4A7 unconjugated
anti-Zyxin (ZYX) (AA 1-572) antibodyZYX 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Zyxin (ZYX) antibodyZYX 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 1-300) antibodyZYX 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (AA 1-573) antibodyZYX 适用: 人, 小鼠 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Zyxin (ZYX) antibodyKD Validated ZYX 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3585 unconjugated Recombinant Antibody
anti-Zyxin (ZYX) (AA 1-572) antibodyZYX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) (Middle Region) antibodyZYX 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zyxin (ZYX) antibodyZYX 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Zyxin (ZYX) (Internal Region) antibodyZYX 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- ZYX (Zyxin (ZYX))
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别名
- Zyxin
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背景
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Synonyms: ZYX, Zyxin, Zyxin-2
Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008],
Gene Name: ZYX
Protein Name: Zyxin
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分子量
- 61 kDa
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基因ID
- 7791
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OMIM
- 602002
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UniProt
- Q15942
抗原
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