Presenilin 1 抗体 (pSer357)
Quick Overview for Presenilin 1 抗体 (pSer357) (ABIN1532166)
抗原
See all Presenilin 1 (PSEN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 323-372, pSer357
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特异性
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PSEN1 (Phospho-Ser357) Antibody detects endogenous levels of PSEN1 only when phosphorylated at Ser357.
PhosphorylationH:S357 M:S357 R:S358
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
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说明
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Unigene-Number: Hs.3260 (NCBI Gene Symbol: PSEN1)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- Presenilin 1 (PSEN1)
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别名
- PSEN1
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背景
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Synonyms: AD3, AD3H, presenilin 1, PS-1, PS1, PSN1, PSNL1, S182 protein
NCBI Gene Symbol: PSEN1
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分子量
- 52 kDa
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基因ID
- 5663
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OMIM
- 104311
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UniProt
- P49768
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途径
- Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
抗原
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