Cyclin D2 抗体 (pThr280)
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北京 101111
Quick Overview for Cyclin D2 抗体 (pThr280) (ABIN1532139)
抗原
See all Cyclin D2 (CCND2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-289, pThr280
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原理
- Cyclin D2 (phospho Thr280) Antibody
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特异性
- Phospho-Cyclin D2 (T280) Polyclonal Antibody detects endogenous levels of Cyclin D2 protein only when phosphorylated at T280.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cyclin D2 around the phosphorylation site of Thr280. AA range:240-289
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亚型
- IgG
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anti-Cyclin D2 (CCND2) (AA 161-288) antibody
CCND2 适用: 人 WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 47-267) antibodyCCND2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 68-278) antibodyCCND2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) antibodyCCND2 适用: 人 ELISA 宿主: 小鼠 Monoclonal CCND2-2620 unconjugated
anti-Cyclin D2 (CCND2) (pThr280) antibodyCCND2 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 215-285) antibodyCCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cyclin D2 (CCND2)
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别名
- Cyclin D2
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背景
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Synonyms: CCND2, G1/S-specific cyclin-D2
Background: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencep
Gene Name: CCND2
Protein Name: G1/S-specific cyclin-D2
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分子量
- 33 kDa
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基因ID
- 894
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OMIM
- 123833
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UniProt
- P30279
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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