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Cadherin 5 抗体 (pTyr731)

This 兔 多克隆 antibody specifically detects Cadherin 5 in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN1532109
发货至: 中国
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Quick Overview for Cadherin 5 抗体 (pTyr731) (ABIN1532109)

抗原

See all Cadherin 5 (CDH5) 抗体
Cadherin 5 (CDH5)

适用

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  • 97
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  • 2
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  • 1
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  • 1
人, 小鼠

宿主

  • 127
  • 29
  • 7
  • 2
兔

克隆类型

  • 115
  • 50
多克隆

标记

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  • 1
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  • 1
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This Cadherin 5 antibody is un-conjugated

应用范围

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  • 7
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 16
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    • 3
    • 3
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    • 1
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    AA 697-746, pTyr731

    原理

    VE-Cadherin (phospho Tyr731) Antibody

    特异性

    Phospho-VE-Cadherin (Y731) Polyclonal Antibody detects endogenous levels of VE-Cadherin protein only when phosphorylated at Y731.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human VE-Cadherin around the phosphorylation site of Tyr731. AA range:697-746

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Cadherin 5 (CDH5)

    别名

    VE-Cadherin

    背景

    Synonyms: CDH5, Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD antigen CD144

    Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015],

    Gene Name: CDH5

    Protein Name: Cadherin-5

    分子量

    87 kDa

    基因ID

    1003

    OMIM

    601120

    UniProt

    P33151

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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