WEE1 抗体 (pSer53)
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Quick Overview for WEE1 抗体 (pSer53) (ABIN1532086)
抗原
See all WEE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-68, pSer53
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原理
- Wee 1 (phospho Ser53) Antibody
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特异性
- Phospho-Wee 1 (S53) Polyclonal Antibody detects endogenous levels of Wee 1 protein only when phosphorylated at S53.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human WEE1 around the phosphorylation site of Ser53. AA range:19-68
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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别名
- WEE1
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背景
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Synonyms: WEE1, Wee1-like protein kinase, WEE1hu, Wee1A kinase
Background: WEE1 G2 checkpoint kinase(WEE1) Homo sapiens This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008],
Gene Name: WEE1
Protein Name: Wee1-like protein kinase
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分子量
- 71 kDa
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基因ID
- 7465
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OMIM
- 193525
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UniProt
- P30291
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
抗原
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