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PKC beta 抗体 (pSer661)

This 兔 多克隆 antibody specifically detects PKC beta in WB, IHC, ELISA 和 IF. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN1532073
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PKC beta 抗体 (pSer661) (ABIN1532073)

抗原

See all PKC beta (PRKCB) 抗体
PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

适用

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人, 大鼠, 小鼠

宿主

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兔

克隆类型

  • 143
  • 27
多克隆

标记

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This PKC beta antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 622-671, pSer661

    原理

    PKC β (phospho Ser661) Antibody

    特异性

    Phospho-PKC β (S661) Polyclonal Antibody detects endogenous levels of PKC β protein only when phosphorylated at S661.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human PKCB around the phosphorylation site of Ser661. AA range:622-671

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    PKC beta (PRKCB) (Protein Kinase C, beta (PRKCB))

    别名

    PKCB

    背景

    Synonyms: PRKCB, PKCB, PRKCB1, Protein kinase C beta type, PKC-B, PKC-beta

    Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stres

    Gene Name: PRKCB

    Protein Name: Protein kinase C beta type

    分子量

    76 kDa

    基因ID

    5579

    OMIM

    176970

    UniProt

    P05771

    途径

    WNT signaling, TCR Signaling, Thyroid Hormone Synthesis, Nuclear Hormone Receptor Binding, Chromatin Binding, Myometrial Relaxation and Contraction, VEGF Signaling, Unfolded Protein Response, BCR Signaling
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