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TYRO3 抗体 (pTyr681, pTyr749)

This 兔 多克隆 antibody specifically detects TYRO3 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1532058
发货至: 中国
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Quick Overview for TYRO3 抗体 (pTyr681, pTyr749) (ABIN1532058)

抗原

See all TYRO3 抗体
TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

适用

  • 99
  • 65
  • 42
  • 4
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 80
  • 23
  • 4
  • 1
兔

克隆类型

  • 67
  • 37
  • 2
多克隆

标记

  • 66
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TYRO3 antibody is un-conjugated

应用范围

  • 72
  • 48
  • 45
  • 20
  • 18
  • 12
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 21
    • 20
    • 13
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 716-765, pTyr681, pTyr749

    原理

    MerTK/Tyro3 (phospho Tyr749/681) Antibody

    特异性

    Phospho-MerTK/Tyro3 (Y749/681) Polyclonal Antibody detects endogenous levels of MerTK/Tyro3 protein only when phosphorylated at Y749/681.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human MER/SKY around the phosphorylation site of Tyr749/681. AA range:716-765

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

    别名

    MER/SKY

    背景

    Synonyms: MERTK, MER, Tyrosine-protein kinase Mer, Proto-oncogene c-Mer, Receptor tyrosine kinase MerTK, TYRO3, BYK, DTK, RSE, SKY, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kin

    Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],

    Gene Name: MERTK/TYRO3

    Protein Name: Tyrosine-protein kinase Mer/Tyrosine-protein kinase receptor TYRO3

    分子量

    110 kDa

    基因ID

    10461, 7301

    OMIM

    268000

    UniProt

    Q12866

    途径

    RTK signaling
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