HSF1 抗体 (pThr142)
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北京 101111
Quick Overview for HSF1 抗体 (pThr142) (ABIN1532015)
抗原
See all HSF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 108-157, pThr142
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原理
- HSF1 (phospho Thr142) Antibody
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特异性
- Phospho-HSF1 (T142) Polyclonal Antibody detects endogenous levels of HSF1 protein only when phosphorylated at T142.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HSF1 around the phosphorylation site of Thr142. AA range:108-157
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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: "ROS Stress Resets Circadian Clocks to Coordinate Pro-Survival Signals." in: PLoS ONE, Vol. 8, Issue 12, pp. e82006, (2013) (PubMed).
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- HSF1 (Heat Shock Factor Protein 1 (HSF1))
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别名
- HSF1
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背景
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Synonyms: HSF1, HSTF1, Heat shock factor protein 1, HSF 1, Heat shock transcription factor 1, HSTF 1
Background: heat shock transcription factor 1(HSF1) Homo sapiens The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phsphorylation, which promotes binding by heat shock protein 90. [provided by RefSeq, Aug 2016],
Gene Name: HSF1
Protein Name: Heat shock factor protein 1
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分子量
- 57 kDa
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基因ID
- 3297
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OMIM
- 140580
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UniProt
- Q00613
抗原
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