Paxillin 抗体 (pTyr118)
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Quick Overview for Paxillin 抗体 (pTyr118) (ABIN1531946)
抗原
See all Paxillin (PXN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 85-134, pTyr118
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原理
- Paxillin (phospho Tyr118) Antibody
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特异性
- Phospho-Paxillin (Y118) Polyclonal Antibody detects endogenous levels of Paxillin protein only when phosphorylated at Y118.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Paxillin around the phosphorylation site of Tyr118. AA range:85-134
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Paxillin (PXN)
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别名
- Paxillin
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背景
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Synonyms: PXN, Paxillin
Background: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011],
Gene Name: PXN
Protein Name: Paxillin
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分子量
- 64 kDa
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基因ID
- 5829
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OMIM
- 602505
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UniProt
- P49023
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途径
- MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
抗原
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