JAK1 抗体 (pTyr1022)
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北京 101111
Quick Overview for JAK1 抗体 (pTyr1022) (ABIN1531881)
抗原
See all JAK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 988-1037, pTyr1022
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原理
- JAK1 (phospho Tyr1022) Antibody
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特异性
- Phospho-JAK1 (Y1022) Polyclonal Antibody detects endogenous levels of JAK1 protein only when phosphorylated at Y1022.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022. AA range:988-1037
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亚型
- IgG
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anti-Janus Kinase 1 (JAK1) (pTyr1022) antibody
JAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyKD Validated JAK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2245 unconjugated Recombinant Antibody
anti-Janus Kinase 1 (JAK1) (AA 172-204), (N-Term) antibodyJAK1 适用: 人 WB 宿主: 兔 Polyclonal RB43809 unconjugated
anti-Janus Kinase 1 (JAK1) (AA 866-899), (C-Term) antibodyJAK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB43812 unconjugated
anti-Janus Kinase 1 (JAK1) (pTyr1022), (pTyr1034) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Janus Kinase 1 (JAK1) antibodyJAK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Janus Kinase 1 (JAK1) (Ser639) antibodyJAK1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF 1:50-200 WB 1:200 - 1:1000. IHC 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- JAK1 (Janus Kinase 1 (JAK1))
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别名
- JAK1
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背景
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Synonyms: JAK1, JAK1A, JAK1B, Tyrosine-protein kinase JAK1, Janus kinase 1, JAK-1
Background: This gene encodes a membrane protein that is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: JAK1
Protein Name: Tyrosine-protein kinase JAK1
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分子量
- 131 kDa
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基因ID
- 3716
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OMIM
- 147795
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UniProt
- P23458
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
抗原
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