ErbB2/Her2 抗体 (pTyr1221)
Quick Overview for ErbB2/Her2 抗体 (pTyr1221) (ABIN1531859)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 1191-1240, pTyr1221
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特异性
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HER2 (Phospho-Tyr1221/Tyr1222) Antibody detects endogenous levels of HER2 only when phosphorylated at Tyr1221/Tyr1222.
PhosphorylationH:Y1221+Y1222 M:Y1222+Y1223 R:Y1223+Y1224
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纯化方法
 - The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
 - > 95 %
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免疫原
 - The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Tyr1221/Tyr1222.
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亚型
 - IgG
 
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应用备注
 - WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
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说明
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Unigene-Number: Hs.446352 (NCBI Gene Symbol: ERBB2)
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限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 mg/mL
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缓冲液
 - phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
 - Sodium azide
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注意事项
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Stable at -20°C for at least 1 year.
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有效期
 - 12 months
 
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
 - HER2
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背景
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Synonyms: C-erbB-2, Epidermal growth factor receptor-related protein, ErbB2, HER2, kinase ErbB2, MLN 19, NEU, NEU proto-oncogene, NGL, p185erbB2, Receptor protein-tyrosine kinase erbB-2, Receptor protein-tyrosine kinase erbB-2 precursor, Tyrosine kinase-type cell s
NCBI Gene Symbol: ERBB2
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分子量
 - 137 kDa
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基因ID
 - 2064
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OMIM
 - 164870
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UniProt
 - P04626
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途径
 - RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
 
抗原
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