HDAC8 抗体 (pSer39)
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Quick Overview for HDAC8 抗体 (pSer39) (ABIN1531858)
抗原
See all HDAC8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 5-54, pSer39
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原理
- HDAC8 (phospho Ser39) Antibody
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特异性
- Phospho-HDAC8 (S39) Polyclonal Antibody detects endogenous levels of HDAC8 protein only when phosphorylated at S39.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human HDAC8 around the phosphorylation site of Ser39. AA range:5-54
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- HDAC8 (Histone Deacetylase 8 (HDAC8))
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别名
- HDAC8
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背景
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Synonyms: HDAC8, HDACL1, CDA07, Histone deacetylase 8, HD8
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Gene Name: HDAC8
Protein Name: Histone deacetylase 8
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分子量
- 41 kDa
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基因ID
- 55869
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OMIM
- 300269
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UniProt
- Q9BY41
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途径
- Cellular Glucan Metabolic Process
抗原
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