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FOXO3 抗体 (pSer253)

The 兔 多克隆 anti-FOXO3 antibody (ABIN1531845) specifically detects FOXO3 in WB, IHC, ELISA 和 IF. The antibody is reactive with 人, 小鼠, 大鼠 和 斑马鱼 samples.
产品编号 ABIN1531845
发货至: 中国
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Quick Overview for FOXO3 抗体 (pSer253) (ABIN1531845)

抗原

See all FOXO3 抗体
FOXO3 (Forkhead Box O3 (FOXO3))

适用

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人, 小鼠, 大鼠, 斑马鱼

宿主

  • 200
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  • 1
兔

克隆类型

  • 141
  • 66
多克隆

标记

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This FOXO3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 220-269, pSer253

    原理

    FoxO3A (phospho Ser253) Antibody

    特异性

    Phospho-FoxO3A (S253) Polyclonal Antibody detects endogenous levels of FoxO3A protein only when phosphorylated at S253.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human FKHRL1 around the phosphorylation site of Ser253. AA range:220-269

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    FOXO3 (Forkhead Box O3 (FOXO3))

    别名

    FKHRL1

    背景

    Synonyms: FOXO3, FKHRL1, FOXO3A, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1

    Background: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008],

    Gene Name: FOXO3

    Protein Name: Forkhead box protein O3

    分子量

    71 kDa

    基因ID

    2309

    OMIM

    602681

    UniProt

    O43524

    途径

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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