Cortactin 抗体 (pTyr421)
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北京 101111
Quick Overview for Cortactin 抗体 (pTyr421) (ABIN1531808)
抗原
See all Cortactin (CTTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 388-437, pTyr421
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原理
- Cortactin (phospho Tyr421) Antibody
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特异性
- Phospho-Cortactin (Y421) Polyclonal Antibody detects endogenous levels of Cortactin protein only when phosphorylated at Y421.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Cortactin around the phosphorylation site of Tyr421. AA range:388-437
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亚型
- IgG
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anti-Cortactin (CTTN) (N-Term) antibody
KO Validated CTTN 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 214-513) antibodyCTTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cortactin (CTTN) antibodyCTTN 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Cortactin (CTTN) (AA 1-105) antibodyCTTN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Cortactin (CTTN) antibodyCTTN 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated
anti-Cortactin (CTTN) antibodyKD Validated CTTN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2335 unconjugated Recombinant Antibody
anti-Cortactin (CTTN) (AA 341-450) antibodyCTTN 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Cortactin (CTTN) (N-Term) antibodyVerified CTTN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 273-302) antibodyCTTN 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33698 unconjugated
anti-Cortactin (CTTN) (AA 1-200) antibodyCTTN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Cortactin (CTTN)
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别名
- Cortactin
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背景
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Synonyms: CTTN, EMS1, Src substrate cortactin, Amplaxin, Oncogene EMS1
Background: cortactin(CTTN) Homo sapiens This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010],
Gene Name: CTTN
Protein Name: Src substrate cortactin
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分子量
- 61 kDa
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基因ID
- 2017
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OMIM
- 164765
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UniProt
- Q14247
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途径
- MAPK Pathway
抗原
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