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beta Catenin 抗体 (pSer37)

The 兔 多克隆 anti-beta Catenin antibody is suitable to detect beta Catenin in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, IF 和 ELISA.
产品编号 ABIN1531784
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for beta Catenin 抗体 (pSer37) (ABIN1531784)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

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多克隆

标记

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This beta Catenin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
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    AA 3-52, pSer37

    原理

    Catenin-β (phospho Ser37) Antibody

    特异性

    Phospho-Catenin-β (S37) Polyclonal Antibody detects endogenous levels of Catenin-β protein only when phosphorylated at S37.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Catenin-beta around the phosphorylation site of Ser37. AA range:3-52

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    Catenin-beta

    背景

    Synonyms: CTNNB1, CTNNB, OK/SW-cl.35, Catenin beta-1, Beta-catenin

    Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],

    Gene Name: CTNNB1 CTNNB OK/SW-cl.35 PRO2286

    Protein Name: Catenin-β, b-catenin, Beta catenin, Beta-catenin, Cadherin associated protein, Catenin (cadherin associated protein), beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CHBCAT, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289

    分子量

    85 kDa

    基因ID

    1499

    OMIM

    116806

    UniProt

    P35222

    途径

    Peptide Hormone Metabolism
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