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SNAIL 抗体 (pSer246)

The 兔 多克隆 anti-SNAIL antibody is suitable to detect SNAIL in samples from 人, 小鼠 和 猴. It has been validated for WB, ELISA, IHC 和 IF.
产品编号 ABIN1531754
发货至: 中国
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Quick Overview for SNAIL 抗体 (pSer246) (ABIN1531754)

抗原

See all SNAIL (SNAI1) 抗体
SNAIL (SNAI1)

适用

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人, 小鼠, 猴

宿主

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兔

克隆类型

  • 87
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多克隆

标记

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This SNAIL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    • 1
    • 1
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    AA 215-264, pSer246

    原理

    SNAI 1 (phospho Ser246) Antibody

    特异性

    Phospho-SNAI 1 (S246) Polyclonal Antibody detects endogenous levels of SNAI 1 protein only when phosphorylated at S246.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human SNAI1 around the phosphorylation site of Ser246. AA range:215-264

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    SNAIL (SNAI1)

    别名

    SNAI1

    背景

    Synonyms: SNAI1, SNAH, Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna

    Background: snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],

    Gene Name: SNAI1

    Protein Name: Zinc finger protein SNAI1(snail)

    分子量

    29 kDa

    基因ID

    6615

    OMIM

    604238

    UniProt

    O95863

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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