Aurora Kinase B 抗体 (pTyr12)
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Quick Overview for Aurora Kinase B 抗体 (pTyr12) (ABIN1531706)
抗原
See all Aurora Kinase B (AURKB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-50, pTyr12
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原理
- ARK-2 (phospho Tyr12) Antibody
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特异性
- Phospho-ARK-2 (Y12) Polyclonal Antibody detects endogenous levels of ARK-2 protein only when phosphorylated at Y12.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human AurB around the phosphorylation site of Tyr12. AA range:1-50
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Aurora Kinase B (AURKB)
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别名
- AurB
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背景
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Synonyms: AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5, Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12
Background: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015],
Gene Name: AURKB
Protein Name: Aurora kinase B,Aurora B
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分子量
- 39 kDa
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基因ID
- 9212
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OMIM
- 604970
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UniProt
- Q96GD4
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途径
- TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades
抗原
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