IL4 Receptor 抗体 (pTyr497)
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北京 101111
Quick Overview for IL4 Receptor 抗体 (pTyr497) (ABIN1531667)
抗原
See all IL4 Receptor (IL4R) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 463-512, pTyr497
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原理
- IL-4Rα (phospho Tyr497) Antibody
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特异性
- Phospho-IL-4Rα (Y497) Polyclonal Antibody detects endogenous levels of IL-4Rα protein only when phosphorylated at Y497.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human IL-4R/CD124 around the phosphorylation site of Tyr497. AA range:463-512
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亚型
- IgG
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anti-Interleukin 4 Receptor (IL4R) (AA 26-233) antibody
IL4R 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 201-300) antibodyIL4R 适用: 人 WB, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 26-232) antibodyIL4R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4B12B12 unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 677-691), (C-Term) antibodyIL4R 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB48074 unconjugated
anti-Interleukin 4 Receptor (IL4R) (AA 1-227) antibodyIL4R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (pTyr497) antibodyIL4R 适用: 人, 小鼠, 大鼠 IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 4 Receptor (IL4R) (Ser540) antibodyIL4R 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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别名
- IL-4R/CD124
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背景
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Synonyms: IL4R, IL4RA, 582J2.1, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD antigen CD124
Background: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
Gene Name: IL4R
Protein Name: Interleukin-4 receptor subunit alpha
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分子量
- 89 kDa
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基因ID
- 3566
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OMIM
- 147781
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UniProt
- P24394
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
抗原
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