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RACGAP1 抗体 (pSer387)

The 兔 多克隆 anti-RACGAP1 antibody (ABIN1531650) specifically detects RACGAP1 in WB, IHC, IF 和 ELISA. The antibody is reactive with 人, 小鼠, 大鼠 和 猴 samples.
产品编号 ABIN1531650
发货至: 中国
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Quick Overview for RACGAP1 抗体 (pSer387) (ABIN1531650)

抗原

See all RACGAP1 抗体
RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 94
  • 5
  • 1
  • 1
兔

克隆类型

  • 84
  • 17
多克隆

标记

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This RACGAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • 抗原表位

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    AA 353-402, pSer387

    原理

    Rac GAP1 (phospho Ser387) Antibody

    特异性

    Phospho-Rac GAP1 (S387) Polyclonal Antibody detects endogenous levels of Rac GAP1 protein only when phosphorylated at S387.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Ser387. AA range:353-402

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

    别名

    GTPase Activating Protein

    背景

    Synonyms: RACGAP1, KIAA1478, MGCRACGAP, Rac GTPase-activating protein 1, Male germ cell RacGap, MgcRacGAP, Protein CYK4 homolg, CYK4, HsCYK-4

    Background: This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016],

    Gene Name: RACGAP1

    Protein Name: Rac GTPase-activating protein 1

    分子量

    71 kDa

    基因ID

    29127

    OMIM

    604980

    UniProt

    Q9H0H5

    途径

    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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