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CDK9 抗体 (pThr186)

The 兔 多克隆 anti-CDK9 antibody (ABIN1531647) specifically detects CDK9 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1531647
发货至: 中国
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Quick Overview for CDK9 抗体 (pThr186) (ABIN1531647)

抗原

See all CDK9 抗体
CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

适用

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人, 小鼠, 大鼠

宿主

  • 114
  • 5
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兔

克隆类型

  • 92
  • 29
多克隆

标记

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This CDK9 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 25
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    AA 152-201, pThr186

    原理

    Cdk9 (phospho Thr186) Antibody

    特异性

    Phospho-Cdk9 (T186) Polyclonal Antibody detects endogenous levels of Cdk9 protein only when phosphorylated at T186.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CDK9 around the phosphorylation site of Thr186. AA range:152-201

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    CDK9 (Cyclin-Dependent Kinase 9 (CDK9))

    别名

    CDK9

    背景

    Synonyms: CDK9, CDC2L4, TAK, Cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit

    Background: cyclin dependent kinase 9(CDK9) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008],

    Gene Name: CDK9

    Protein Name: Cyclin-dependent kinase 9

    分子量

    42 kDa

    基因ID

    1025

    OMIM

    603251

    UniProt

    P50750

    途径

    Cell Division Cycle
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