CDK9 抗体 (pThr186)
Our Local Distributor
北京 101111
Quick Overview for CDK9 抗体 (pThr186) (ABIN1531647)
抗原
See all CDK9 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 152-201, pThr186
-
原理
- Cdk9 (phospho Thr186) Antibody
-
特异性
- Phospho-Cdk9 (T186) Polyclonal Antibody detects endogenous levels of Cdk9 protein only when phosphorylated at T186.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
纯度
- > 95 %
-
免疫原
- The antiserum was produced against synthesized peptide derived from human CDK9 around the phosphorylation site of Thr186. AA range:152-201
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C/1 year
-
有效期
- 12 months
-
-
- CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
-
别名
- CDK9
-
背景
-
Synonyms: CDK9, CDC2L4, TAK, Cyclin-dependent kinase 9, C-2K, Cell division cycle 2-like protein kinase 4, Cell division protein kinase 9, Serine/threonine-protein kinase PITALRE, Tat-associated kinase complex catalytic subunit
Background: cyclin dependent kinase 9(CDK9) Homo sapiens The protein encoded byThis gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008],
Gene Name: CDK9
Protein Name: Cyclin-dependent kinase 9
-
分子量
- 42 kDa
-
基因ID
- 1025
-
OMIM
- 603251
-
UniProt
- P50750
-
途径
- Cell Division Cycle
抗原
-