STAT5 A/B 抗体 (pSer725, pSer730)
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北京 101111
Quick Overview for STAT5 A/B 抗体 (pSer725, pSer730) (ABIN1531635)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 696-745, pSer725, pSer730
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原理
- Stat5a/b (phospho Ser726/731) Antibody
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特异性
- Phospho-Stat5a/b (S726/731) Polyclonal Antibody detects endogenous levels of Stat5a/b protein only when phosphorylated at S726/731.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human STAT5A/B around the phosphorylation site of Ser725/730. AA range:696-745
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亚型
- IgG
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anti-STAT5 A/B (STAT5 A/B) (pTyr694) antibody
STAT5 A/B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STAT5 A/B (STAT5 A/B) (pTyr694) antibodySTAT5 A/B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-STAT5 A/B (STAT5 A/B) (pTyr694), (pTyr699) antibodySTAT5 A/B 适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
anti-STAT5 A/B (STAT5 A/B) (C-Term) antibodySTAT5 A/B 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-STAT5 A/B (STAT5 A/B) (pSer726), (pSer731) antibodySTAT5 A/B 适用: 人 WB, DB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- STAT5 A/B
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别名
- STAT5A/B
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背景
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Synonyms: STAT5A, STAT5, Signal transducer and activator of transcription 5A, STAT5B, Signal transducer and activator of transcription 5B
Background: The protein encoded byThis gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been
Gene Name: STAT5A/STAT5B
Protein Name: Signal transducer and activator of transcription 5A/B
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分子量
- 90 kDa
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基因ID
- 6776, 6777
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OMIM
- 601511
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UniProt
- P42229
抗原
-
