MCM4 抗体 (pSer54)
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Quick Overview for MCM4 抗体 (pSer54) (ABIN1531581)
抗原
See all MCM4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-69, pSer54
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原理
- MCM4 (phospho Ser54) Antibody
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特异性
- Phospho-MCM4 (S54) Polyclonal Antibody detects endogenous levels of MCM4 protein only when phosphorylated at S54.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human MCM4 around the phosphorylation site of Ser54. AA range:20-69
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亚型
- IgG
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anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibody
MCM4 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 1-863) antibodyMCM4 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 361-677) antibodyMCM4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 2-141) antibodyMCM4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 750-800) antibodyMCM4 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 325-375) antibodyMCM4 适用: 人 IHC 宿主: 山羊 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 325-375) antibodyMCM4 适用: 人, 小鼠 WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) (AA 750-800) antibodyMCM4 适用: 人, 小鼠 WB, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Deficient 4 (MCM4) antibodyMCM4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4960 unconjugated Recombinant Antibody
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))
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别名
- MCM4
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背景
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Synonyms: MCM4, CDC21, DNA replication licensing factor MCM4, CDC21 homolog, P1-CDC21
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcri
Gene Name: MCM4
Protein Name: DNA replication licensing factor MCM4
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分子量
- 96 kDa
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基因ID
- 4173
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OMIM
- 602638
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UniProt
- P33991
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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