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Integrin beta 2 抗体 (pThr758)

This 兔 多克隆 antibody specifically detects Integrin beta 2 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531540
发货至: 中国
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Quick Overview for Integrin beta 2 抗体 (pThr758) (ABIN1531540)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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人, 小鼠, 大鼠

宿主

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兔

克隆类型

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  • 2
多克隆

标记

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This Integrin beta 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 720-769, pThr758

    原理

    Integrin β2 (phospho Thr758) Antibody

    特异性

    Phospho-Integrin β2 (T758) Polyclonal Antibody detects endogenous levels of Integrin β2 protein only when phosphorylated at T758.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human CD18/ITGB2 around the phosphorylation site of Thr758. AA range:720-769

    亚型

    IgG
  • 应用备注

    WB 1:500-2000,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    CD18/ITGB2

    背景

    Synonyms: ITGB2, CD18, MFI7, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta, Complement receptor C3 subunit beta, CD antigen CD18

    Background: This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],

    Gene Name: ITGB2

    Protein Name: Integrin beta-2

    分子量

    84 kDa

    基因ID

    3689

    OMIM

    116920

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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