CASR 抗体 (pThr888)
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北京 101111
Quick Overview for CASR 抗体 (pThr888) (ABIN1531528)
抗原
See all CASR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 854-903, pThr888
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原理
- CaSR (phospho Thr888) Antibody
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特异性
- Phospho-CaSR (T888) Polyclonal Antibody detects endogenous levels of CaSR protein only when phosphorylated at T888.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor around the phosphorylation site of Thr888. AA range:854-903
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亚型
- IgG
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anti-Calcium-Sensing Receptor (CASR) (AA 874-1088) antibody
CASR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 121-220) antibodyCASR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) antibodyCASR 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 216-229), (Extracellular), (N-Term) antibodyKO Validated CASR 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 926-1078) antibodyCASR 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 260-287) antibodyCASR 适用: 小鼠 WB 宿主: 兔 Polyclonal RB41198 unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 1-100) antibody (Atto 594)CASR 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 594
anti-Calcium-Sensing Receptor (CASR) (AA 1-100) antibody (APC)CASR 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal APC
anti-Calcium-Sensing Receptor (CASR) (AA 1-100) antibodyCASR 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calcium-Sensing Receptor (CASR) (AA 1-100) antibody (Atto 488)CASR 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal Atto 488
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应用备注
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- CASR (Calcium-Sensing Receptor (CASR))
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别名
- Calcium Sensing Receptor
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背景
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Synonyms: CASR, GPRC2A, PCAR1, Extracellular calcium-sensing receptor, CaSR, Parathyroid cell calcium-sensing receptor, PCaR1
Background: The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008],
Gene Name: CASR
Protein Name: Extracellular calcium-sensing receptor
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分子量
- 120 kDa
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基因ID
- 846
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OMIM
- 145980
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UniProt
- P41180
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途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
抗原
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