PKC delta 抗体 (pThr505)
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北京 101111
Quick Overview for PKC delta 抗体 (pThr505) (ABIN1531463)
抗原
See all PKC delta (PKCd) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 471-520, pThr505
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原理
- PKC δ (phospho Thr507) Antibody
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特异性
- Phospho-PKC δ (T507) Polyclonal Antibody detects endogenous levels of PKC δ protein only when phosphorylated at T507.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PKC delta around the phosphorylation site of Thr505. AA range:471-520
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亚型
- IgG
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anti-Protein Kinase C, delta (PKCd) (AA 477-676) antibody
PKCd 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 小鼠 WB, IF (p), FACS 宿主: 兔 Monoclonal 24GB4485 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (AA 4-676) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6A2 unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2410 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (pSer645) antibodyPKCd 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (pTyr64) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (C-Term) antibodyPKCd 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 1-676) antibodyPKCd 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
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别名
- PKC delta
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背景
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Synonyms: PRKCD, Protein kinase C delta type, Tyrosine-protein kinase PRKCD, nPKC-delta
Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells.The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008],
Gene Name: PRKCD
Protein Name: Protein kinase C delta type
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分子量
- 77 kDa
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基因ID
- 5580
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OMIM
- 176977
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UniProt
- Q05655
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途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
抗原
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