NKX2-1 抗体 (pSer113)
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北京 101111
Quick Overview for NKX2-1 抗体 (pSer113) (ABIN1531400)
抗原
See all NKX2-1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 79-128, pSer113
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原理
- p23 (phospho Ser113) Antibody
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特异性
- Phospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human TEBP around the phosphorylation site of Ser113. AA range:79-128
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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别名
- TEBP
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背景
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Synonyms: PTGES3, P23, TEBP, Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, cPGES, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23
Background: This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016],
Gene Name: PTGES3
Protein Name: Prostaglandin E synthase 3
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分子量
- 18 kDa
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基因ID
- 10728
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OMIM
- 607061
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UniProt
- Q15185
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
抗原
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