RYR2 抗体 (pSer2808)
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Quick Overview for RYR2 抗体 (pSer2808) (ABIN1531389)
抗原
See all RYR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2774-2823, pSer2808
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原理
- RyR-2 (phospho Ser2808) Antibody
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特异性
- Phospho-RyR-2 (S2808) Polyclonal Antibody detects endogenous levels of RyR-2 protein only when phosphorylated at S2808.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human RyR2 around the phosphorylation site of Ser2808. AA range:2774-2823
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亚型
- IgG
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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别名
- RyR2
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背景
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Synonyms: RYR2, Ryanodine receptor 2, RYR-2, RyR2, hRYR-2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, Type 2 ryanodine receptor
Background: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008],
Gene Name: RYR2
Protein Name: Ryanodine receptor 2
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分子量
- 564 kDa
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基因ID
- 6262
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OMIM
- 180902
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UniProt
- Q92736
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途径
- Myometrial Relaxation and Contraction
抗原
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