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RYR2 抗体 (pSer2808)

This 兔 多克隆 antibody specifically detects RYR2 in ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1531389
发货至: 中国
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Quick Overview for RYR2 抗体 (pSer2808) (ABIN1531389)

抗原

See all RYR2 抗体
RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

适用

  • 57
  • 32
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  • 1
人, 小鼠, 大鼠

宿主

  • 56
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兔

克隆类型

  • 56
  • 1
多克隆

标记

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  • 2
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This RYR2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 13
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    • 1
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    AA 2774-2823, pSer2808

    原理

    RyR-2 (phospho Ser2808) Antibody

    特异性

    Phospho-RyR-2 (S2808) Polyclonal Antibody detects endogenous levels of RyR-2 protein only when phosphorylated at S2808.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human RyR2 around the phosphorylation site of Ser2808. AA range:2774-2823

    亚型

    IgG
  • 应用备注

    IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

    别名

    RyR2

    背景

    Synonyms: RYR2, Ryanodine receptor 2, RYR-2, RyR2, hRYR-2, Cardiac muscle ryanodine receptor, Cardiac muscle ryanodine receptor-calcium release channel, Type 2 ryanodine receptor

    Background: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008],

    Gene Name: RYR2

    Protein Name: Ryanodine receptor 2

    分子量

    564 kDa

    基因ID

    6262

    OMIM

    180902

    UniProt

    Q92736

    途径

    Myometrial Relaxation and Contraction
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