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RYR2 抗体 (pSer2814)

The 兔 多克隆 anti-RYR2 antibody is suitable to detect RYR2 in samples from 人 和 犬. It has been validated for IHC 和 WB.
产品编号 ABIN6256236
发货至: 中国
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Quick Overview for RYR2 抗体 (pSer2814) (ABIN6256236)

抗原

See all RYR2 抗体
RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

适用

  • 56
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人, 犬

宿主

  • 55
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克隆类型

  • 55
  • 1
多克隆

标记

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This RYR2 antibody is un-conjugated

应用范围

  • 23
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Immunohistochemistry (IHC), Western Blotting (WB)
  • 抗原表位

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    pSer2814

    特异性

    Phospho-RYR2( Ser2814) Antibody detects endogenous levels of RYR2.

    交叉反应

    犬, 人

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human RYR2 around the phosphorylation site of Ser2814.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

    别名

    RYR2

    背景

    Description: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.

    Gene: RYR2

    分子量

    564 kDa

    基因ID

    6262

    UniProt

    Q92736

    途径

    Myometrial Relaxation and Contraction
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