RYR2 抗体 (pSer2814)
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北京 101111
Quick Overview for RYR2 抗体 (pSer2814) (ABIN6256236)
抗原
See all RYR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer2814
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特异性
- Phospho-RYR2( Ser2814) Antibody detects endogenous levels of RYR2.
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交叉反应
- 犬, 人
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human RYR2 around the phosphorylation site of Ser2814.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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别名
- RYR2
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背景
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Description: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
Gene: RYR2
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分子量
- 564 kDa
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基因ID
- 6262
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UniProt
- Q92736
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途径
- Myometrial Relaxation and Contraction
抗原
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