Ret Proto-Oncogene 抗体 (pTyr1015)
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Quick Overview for Ret Proto-Oncogene 抗体 (pTyr1015) (ABIN1531387)
抗原
See all Ret Proto-Oncogene (RET) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 991-1040, pTyr1015
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原理
- Ret (phospho Tyr1015) Antibody
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特异性
- Phospho-Ret (Y1015) Polyclonal Antibody detects endogenous levels of Ret protein only when phosphorylated at Y1015.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Ret around the phosphorylation site of Tyr1015. AA range:991-1040
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亚型
- IgG
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anti-Ret Proto-Oncogene (RET) (AA 702-848) antibody
RET 适用: 人 IHC 宿主: 小鼠 Monoclonal RET-2795 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 29-304) antibodyRET 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 702-848) antibodyRET 适用: 人 ELISA 宿主: 小鼠 Monoclonal RET-2663 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 1-1072) antibodyRET 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 541-553), (Extracellular), (N-Term) antibodyRET 适用: 人 WB, IHC, IF, FACS, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (AA 152-182), (N-Term) antibodyRET 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00705 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 1012-1042), (C-Term) antibodyRET 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01561 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 361-458) antibodyRET 适用: 人 ELISA, PLA 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Ret Proto-Oncogene (RET) (AA 1001-1114) antibodyRET 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ret Proto-Oncogene (RET) (pTyr905) antibodyRET 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Ret Proto-Oncogene (RET)
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别名
- Ret
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背景
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Synonyms: RET, CDHF12, CDHR16, PTC, RET51, Proto-oncogene tyrosine-protein kinase receptor Ret, Cadherin family member 12, Proto-oncogene c-Ret
Background: ret proto-oncogene(RET) Homo sapiens This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008],
Gene Name: RET
Protein Name: Proto-oncogene tyrosine-protein kinase receptor Ret
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分子量
- 124 kDa
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基因ID
- 5979
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OMIM
- 114500
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UniProt
- P07949
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途径
- RTK signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation
抗原
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