Estrogen Receptor alpha 抗体 (pTyr537)
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Quick Overview for Estrogen Receptor alpha 抗体 (pTyr537) (ABIN1531313)
抗原
See all Estrogen Receptor alpha (ESR1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 501-550, pTyr537
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特异性
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Estrogen Receptor-alpha (Phospho-Tyr537) Antibody detects endogenous levels of Estrogen Receptor-alpha only when phosphorylated at Tyr537.
PhosphorylationH:Y537 M:Y541 M:Y542
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha around the phosphorylation site of Tyr537.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
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说明
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Unigene-Number: Hs.208124 (NCBI Gene Symbol: ESR1)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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别名
- Estrogen Receptor-alpha
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背景
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Synonyms: ER, ESR, ESR1, ESTR, ESTRA, Estradiol receptor, Estrogen receptor, NR3A1
NCBI Gene Symbol: ESR1
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分子量
- 66 kDa
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基因ID
- 2099
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OMIM
- 133430
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UniProt
- P03372
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途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
抗原
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