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OPRK1 抗体 (pSer369)

The 兔 多克隆 anti-OPRK1 antibody (ABIN1531292) specifically detects OPRK1 in WB, ELISA, IHC 和 IF. The antibody is reactive with 大鼠 和 小鼠 samples.
产品编号 ABIN1531292
发货至: 中国
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Quick Overview for OPRK1 抗体 (pSer369) (ABIN1531292)

抗原

See all OPRK1 抗体
OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

适用

  • 55
  • 43
  • 30
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
大鼠, 小鼠

宿主

  • 75
  • 2
  • 1
  • 1
兔

克隆类型

  • 68
  • 11
多克隆

标记

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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
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  • 1
  • 1
  • 1
  • 1
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This OPRK1 antibody is un-conjugated

应用范围

  • 53
  • 23
  • 16
  • 14
  • 9
  • 8
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 11
    • 8
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 331-380, pSer369

    原理

    KOR-1 (phospho Ser369) Antibody

    特异性

    Phospho-KOR-1 (S369) Polyclonal Antibody detects endogenous levels of KOR-1 protein only when phosphorylated at S369.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from mouse KOR-1 around the phosphorylation site of Ser369. AA range:331-380

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

    别名

    KOR-1

    背景

    Synonyms: OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1

    Background: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

    Gene Name: OPRK1

    Protein Name: Kappa-type opioid receptor

    分子量

    42 kDa

    UniProt

    P41145
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