PTK2B 抗体 (pTyr881)
Quick Overview for PTK2B 抗体 (pTyr881) (ABIN1531239)
抗原
See all PTK2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 847-896, pTyr881
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特异性
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PYK2 (Phospho-Tyr881) Antibody detects endogenous levels of PYK2 only when phosphorylated at Tyr881.
PhosphorylationH:Y881 M:Y881 R:Y881
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human PYK2 around the phosphorylation site of Tyr881.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000
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说明
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Unigene-Number: Hs.491322 (NCBI Gene Symbol: PTK2B)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))
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别名
- PYK2
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背景
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Synonyms: CADTK, CAK beta, Calcium-dependent tyrosine kinase, Cell adhesion kinase beta, FADK 2, FAK2, Focal adhesion kinase 2, kinase Pyk2, Proline-rich tyrosine kinase 2, Protein tyrosine kinase 2 beta, PTK2B, RAFTK, Related adhesion focal tyrosine kinase
NCBI Gene Symbol: PTK2B
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分子量
- 115 kDa
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基因ID
- 2185
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OMIM
- 601212
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UniProt
- Q14289
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling
抗原
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