BCAR1 抗体 (pTyr410)
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北京 101111
Quick Overview for BCAR1 抗体 (pTyr410) (ABIN1531233)
抗原
See all BCAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 376-425, pTyr410
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原理
- p130 Cas (phospho Tyr410) Antibody
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特异性
- Phospho-p130 Cas (Y410) Polyclonal Antibody detects endogenous levels of p130 Cas protein only when phosphorylated at Y410.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr410. AA range:376-425
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亚型
- IgG
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应用备注
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- BCAR1 (Breast Cancer Anti-Estrogen Resistance 1 (BCAR1))
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别名
- p130 Cas
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背景
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Synonyms: BCAR1, CAS, CASS1, CRKAS, Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas
Background: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM, May 2009],
Gene Name: BCAR1
Protein Name: Breast cancer anti-estrogen resistance protein 1
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分子量
- 93 kDa
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基因ID
- 9564
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OMIM
- 602941
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UniProt
- P56945
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
抗原
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