APP 抗体 (pThr743)
Quick Overview for APP 抗体 (pThr743) (ABIN1531173)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 711-760, pThr743
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特异性
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Amyloid beta A4 (Phospho-Thr743/668) Antibody detects endogenous levels of Amyloid beta A4 only when phosphorylated at Thr743/668.
PhosphorylationH:T743 M:T743 R:T743
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纯化方法
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Amyloid beta A4 around the phosphorylation site of Thr743/668.
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亚型
- IgG
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应用备注
- WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000
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说明
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Unigene-Number: Hs.434980 (NCBI Gene Symbol: APP)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable at -20°C for at least 1 year.
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有效期
- 12 months
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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背景
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Synonyms: A4, ABPP, AD1, APP, APPI, Alzheimer's disease amyloid protein, Amyloid beta A4 protein precursor, Beta-amyloid protein 40, Beta-amyloid protein 42, C31, C83, CVAP, Cerebral vascular amyloid peptide, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), P3(40), P3(
NCBI Gene Symbol: APP
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分子量
- 86 kDa
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基因ID
- 351
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OMIM
- 104300
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UniProt
- P05067
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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