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APP 抗体 (pThr743)

This 兔 多克隆 anti-APP antibody specifically detects APP in WB, ELISA, IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1531173
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APP 抗体 (pThr743) (ABIN1531173)

抗原

See all APP 抗体
APP (Amyloid beta (A4) Precursor Protein (APP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This APP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 711-760, pThr743

    特异性

    Amyloid beta A4 (Phospho-Thr743/668) Antibody detects endogenous levels of Amyloid beta A4 only when phosphorylated at Thr743/668.

    PhosphorylationH:T743 M:T743 R:T743

    纯化方法

    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Amyloid beta A4 around the phosphorylation site of Thr743/668.

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:10000

    说明

    Unigene-Number: Hs.434980 (NCBI Gene Symbol: APP)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable at -20°C for at least 1 year.

    有效期

    12 months
  • 抗原

    APP (Amyloid beta (A4) Precursor Protein (APP))

    背景

    Synonyms: A4, ABPP, AD1, APP, APPI, Alzheimer's disease amyloid protein, Amyloid beta A4 protein precursor, Beta-amyloid protein 40, Beta-amyloid protein 42, C31, C83, CVAP, Cerebral vascular amyloid peptide, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), P3(40), P3(

    NCBI Gene Symbol: APP

    分子量

    86 kDa

    基因ID

    351

    OMIM

    104300

    UniProt

    P05067

    途径

    Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
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