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Caspase 3 抗体

CASP3 适用: 人 IP 宿主: 小鼠 Monoclonal AMI-3-1-11 unconjugated
产品编号 ABIN1526064
发货至: 中国
  • 抗原 See all Caspase 3 (CASP3) 抗体
    Caspase 3 (CASP3)
    适用
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    宿主
    • 280
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    小鼠
    克隆类型
    • 274
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    单克隆
    标记
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    This Caspase 3 antibody is un-conjugated
    应用范围
    • 252
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    Immunoprecipitation (IP)
    特异性
    This antibody immunoprecipitates Caspase-3.
    交叉反应 (详细)
    Species reactivity (tested):Human
    纯化方法
    Protein A agarose
    克隆位点
    AMI-3-1-11
    亚型
    IgG2a
    Top Product
    Discover our top product CASP3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    储存液
    Without preservative
  • 抗原
    Caspase 3 (CASP3)
    别名
    Caspase-3 (CASP3 产品)
    别名
    CPP32 antibody, CPP32B antibody, SCA-1 antibody, A830040C14Rik antibody, AC-3 antibody, Apopain antibody, CC3 antibody, Caspase-3 antibody, Lice antibody, Yama antibody, mldy antibody, xcpp32 antibody, casp3 antibody, zgc:100890 antibody, CASP-3 antibody, caspase-3 antibody, caspase 3 antibody, caspase 3 S homeolog antibody, caspase 3, apoptosis-related cysteine peptidase a antibody, caspase 3, apoptosis-related cysteine peptidase antibody, CASP3 antibody, Casp3 antibody, casp3.S antibody, casp3a antibody
    背景
    Caspase-3 (also known as CPP32, Yama, apopain) is a key member of the caspase family of cysteine proteases. Caspase-3 ex ists in cells as an inactive 32 kDa proenzyme. During apoptosis procaspase-3 is processed at aspartate residues by self-proteolysis and/or cleavage by upstream caspases, such as caspase-6, 8, or 9. The processed form of caspase-3 consists of large (17 kDa) and small (12 kDa) subun its which associate to form the active tetrameric enzyme tetramer (a pair of heterodimers). The active caspa se-3 proteolytically cleaves and activates other caspases, as well as relevant targets in the cells (e.g., PARP, SREBPs, and DFF). Activation of procaspase-3 stands at a point of convergence for the two major types of apoptosis signaling pathways-those linked to cell surface death receptors and those linked to mitochondrial release of cytochrome c.Synonyms: Apopain, CASP-3, CASP3, CPP-32, CPP32, Cysteine protease CPP32, SCA-1, SCA1, SREBP cleavage activity 1, Yama protein
    基因ID
    836
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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