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TIMP2 抗体 (AA 100-200)

This anti-TIMP2 antibody is a 兔 多克隆 antibody detecting TIMP2 in WB, IHC 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1513608
发货至: 中国

Quick Overview for TIMP2 抗体 (AA 100-200) (ABIN1513608)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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宿主

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克隆类型

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  • 84
多克隆

标记

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This TIMP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 38
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    AA 100-200

    序列

    VSLDVGGKKE YLIAGKAEGD GKMHITLCDF IVPWDTLSTT QKKSLNHRYQ MGCECKITRC PMIPCYISSP DECLWMDWVT EKNINGHQAK FFACIKRSDG S

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TIMP2 (NP_003246.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Zhang, Sun, Wang, Yang, Yang, Zhang, Luo, Wang, Jiang, Zeng, Cai, Bai: "Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 25, Issue 3, pp. 715-727, (2017) (PubMed).

  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.,TIMP2,CSC-21K,DDC8,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,TIMP2

    分子量

    24 kDa

    基因ID

    7077

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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