NeuN 抗体 (AA 1-220)
Quick Overview for NeuN 抗体 (AA 1-220) (ABIN1513254)
抗原
See all NeuN (RBFOX3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-220
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序列
- MAQPYPPAQY PPPPQNGIPA EYAPPPPHPT QDYSGQTPVP TEHGMTLYTP AQTHPEQPGS EASTQPIAGT QTVPQTDEAA QTDSQPLHPS DPTEKQQPKR LHVSNIPFRF RDPDLRQMFG QFGKILDVEI IFNERGSKGF GFVTFETSSD ADRAREKLNG TIVEGRKIEV NNATARVMTN KKTGNPYTNG WKLNPVVGAV YGPEFYAVTG FPYPTTGTAV
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human NeuN (NP_001076044.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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: "SMAD4 is Involved in the Development of Endotoxin Tolerance in Microglia." in: Cellular and molecular neurobiology, Vol. 36, Issue 5, pp. 777-88, (2017) (PubMed).
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: "SMAD4 is Involved in the Development of Endotoxin Tolerance in Microglia." in: Cellular and molecular neurobiology, Vol. 36, Issue 5, pp. 777-88, (2017) (PubMed).
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- NeuN (RBFOX3) (RNA Binding Protein, Fox-1 Homolog 3 (RBFOX3))
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别名
- RBFOX3
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背景
- This gene encodes a member of the RNA-binding FOX protein family which is involved in the regulation of alternative splicing of pre-mRNA. The protein has an N-terminal proline-rich region, an RNA recognition motif (RRM) domain, and a C-terminal alanine-rich region. This gene produces the neuronal nuclei (NeuN) antigen that has been widely used as a marker for post-mitotic neurons. This gene has its highest expression in the central nervous system and plays a prominent role in neural tissue development and regulation of adult brain function. Mutations in this gene have been associated with numerous neurological disorders. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.,FOX-3,FOX3,HRNBP3,NEUN,NeuN,RBFOX3,Epigenetics & Nuclear Signaling,Transcription Factors,Neuroscience,Cell Type Marker,Neuron marker,RBFOX3
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分子量
- 33 kDa/35 kDa
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基因ID
- 146713
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UniProt
- A6NFN3
抗原
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