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LRP5 抗体 (AA 1000-1250)

This anti-LRP5 antibody is a 兔 多克隆 antibody detecting LRP5 in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN1513164
发货至: 中国

Quick Overview for LRP5 抗体 (AA 1000-1250) (ABIN1513164)

抗原

See all LRP5 抗体
LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

适用

  • 60
  • 50
  • 25
  • 1
  • 1

宿主

  • 67
  • 7
  • 2
  • 1

克隆类型

  • 71
  • 6
多克隆

标记

  • 32
  • 4
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  • 4
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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This LRP5 antibody is un-conjugated

应用范围

  • 38
  • 28
  • 26
  • 19
  • 13
  • 7
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 15
    • 8
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    • 3
    • 2
    • 2
    • 2
    • 2
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    • 1
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    AA 1000-1250

    序列

    IKRAKDDGTQ PFVLTSLSQG QNPDRQPHDL SIDIYSRTLF WTCEATNTIN VHRLSGEAMG VVLRGDRDKP RAIVVNAERG YLYFTNMQDR AAKIERAALD GTEREVLFTT GLIRPVALVV DNTLGKLFWV DADLKRIESC DLSGANRLTL EDANIVQPLG LTILGKHLYW IDRQQQMIER VEKTTGDKRT RIQGRVAHLT GIHAVEEVSL EEFSAHPCAR DNGGCSHICI AKGDGTPRCS CPVHLVLLQN L

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1000-1250 of human LRP5 (NP_002326.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

  • 抗原

    LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))

    别名

    LRP5

    背景

    This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.,LRP5,BMND1,EVR1,EVR4,HBM,LR3,LRP-5,LRP7,OPPG,OPS,OPTA1,VBCH2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Extracellular Matrix,Bone,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Stem Cells,Cardiovascular,Lipids,LRP5

    分子量

    179 kDa

    基因ID

    4041

    UniProt

    O75197

    途径

    WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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