IDO1 抗体 (AA 204-403)
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北京 101111
Quick Overview for IDO1 抗体 (AA 204-403) (ABIN1513093)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 204-403
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序列
- ASCLEKALQV FHQIHDHVNP KAFFSVLRIY LSGWKGNPQL SDGLVYEGFW EDPKEFAGGS AGQSSVFQCF DVLLGIQQTA GGGHAAQFLQ DMRRYMPPAH RNFLCSLESN PSVREFVLSK GDAGLREAYD ACVKALVSLR SYHLQIVTKY ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 204-403 of human IDO1 (NP_002155.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze / thaw cycles
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO1
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背景
- This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.,IDO1,IDO,IDO-1,INDO,indoleamine 2,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Cardiovascular,IDO1
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分子量
- 45 kDa
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基因ID
- 3620
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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